In silico fragment-based hit identification for efficient discovery of new cosmetic ingredient
Smart chemical libraries from Prestwick Chemical: powerful tools for high-quality hit discovery
Fragment pharmacophore-based in silico screening: a powerful approach for efficient lead discovery
CD41 (Itga2b) identifies lymph node lymphatic endothelial cells activated by RANKL
The Prestwick Chemical Library®, a valuable tool for screening
Alpha-7 nicotinic acetylcholine receptor modulators and uses thereof
Heteroatom containing deoxyuridine triphosphatase inhibitors
Structure-based discovery of novel NIK inhibitors
Comparison of hit discovery approaches. Case study: NIK inhibitors
Pharmacophore-based characterization of the Prestwick Chemical Library®
High throughput behevioral sleep assay for larval zebrafish
In vivo characterization of a novel highly potent GPR88 agonist
Screening for neuroprotective activity in a Drosophila model of Parkinson’s disease using a new Prestwick Drosophila library
Deoxyuridine triphosphatase inhibitors
Alpha7 nicotinic acetylcholine receptor modulators and uses thereof
2-(3-Aminoaryl) amino-4-aryl-thiazoles and their use as c-Kit inhibitors
Chemical library screening using a SPR-Based inhibition in solution assay: simulations and experimental validation
BNC375, A novel positive allosteric modulator of the α7 nicotinic acetylcholine receptor, exhibits cognitive enhancement in rodent behavioural models
7-Oxo-thiazolopyridine carbonic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease
Heteroaryl hydroxamic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease
Pyrimidin-4-one derivatives and their use in the treatment, amelioration or prevention of a viral disease
7-Oxo-4,7 -dihydro- pyrazolo [1,5-a] pyrimidine derivatives which are useful in the treatment, amelioration or prevention of a viral disease
Positive allosteric modulators of the alpha 7 nicotinic acetylcholine receptor and uses thereof
Expeditious route towards (+/-)-desethyleburnamonine, a precursor of (+/-) Vindeburnol
Novel oxime derivatives and their use as allosteric modulators of metabotropic glutamate receptors
New phenylhydrazone derivatives and their use as pharmaceuticals
Small molecule inhibitors of influenza A and B virus and respiratory syncytial virus replication
9-Substituted-β-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials
Styrylquinolines, their process of preparation and their therapeutic uses
Styrylquinolines, their process of preparation and their therapeutic uses
Styrylquinolines, their process of preparation and their therapeutic uses
2-Aminoaryloxazole compounds as tyrosine kinase inhibitors
A new quinoline family of HIV-1 integrase inhibitors acting on HIV-1 mutants selected by integrase strand transfer inhibitors
New derivatives of 14,15-dihydro-20,21-dinoreburnamin-14-ol as potent antidepressants
Novel 7-substituted derivatives of 3-carboxy-oxadiazino-quinolones, preparation thereof and use thereof as anti-bacterial agents
Use of a carbonic anhydrase inhibitor for preparation of a drug for treating skeletal muscle degeneration
Use of a tricyclic compound for preparing a medicine for treating skeletal muscle degeneration
Cyclic-alkylaminederivatives as inhibitors of the interaction between Mdm2 and p53
Pyridazinone compounds as calcilytics
6-Heteroarylpyridoindolone derivatives, their preparation and therapeutic use thereof
Inhibitors of the interaction between Mdm2 and p53
Aminoaryl substituted five-membered ring heterocyclic compounds for the treatment of diseases
Novel pyrrolodihydroisoquinolines
Novel Pyrrolodihydroisoquinolines as PDE10 inhibitors
Prodrug constructs of pyrimidone compounds as calcilytics
2-Aminoaryloxazole compounds as tyrosine kinase inhibitors
2-(3-Substituted-aryl) amino-4-aryl-thiazoles as tyrosine kinase inhibitors
Pyrrolodihydroisoquinolines as PDE10 inhibitors
Derivatives of 14,15-dihydro 20.21-dinoreburnamenin-14-ol, and applications thereof
6-Substituted pyridoindolone derivatives production and therapeutic use thereof
2-(3-Aminoaryl)amino-4-aryl-thiazoles and their use as c-Kit inhibitors
Derivatives of glycinergic R(+)-2-amino-3-hydroxypropanoic acid
3-Phenyl substituted pyridoindolone, preparation and their therapeutic use thereof
Piperidin-2,6-dione pamoate salts and their use for the treatment of stress-related affective disorders