Hit to Lead expansion and Lead optimization services

Validating hits, optimizing leads into drug candidates represents often the bottleneck of drug development programs. Today´s challenge consists of shortening the optimization process, improving quality of compound flow and project management, thus reducing overall costs.

Thanks to their expertise in traditional medicinal chemistry and particularly in lead optimization, Prestwick´s team of medicinal chemists and pharmacists can be of great assistance to achieve these goals. They develop medicinal chemistry strategies tailored to clients needs, taking into account ADME and toxicity issues to minimize time and maximize results (in average 18 months from inception to acceptable drug candidate). Prestwick Chemical will consider various possible collaborations including ´no string attached´ programs (FTE based) or objective driven programs (minimum base fee + milestones)...


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