Prestwick Chemical has been created in 1999 from the joint effort of Prof. Camille G. Wermuth, PhD, PharmD., and Dr Kathleen Clarence Smith, PhD, MD. Management has since been extended, though Prestwick Chemical aims at staying a lean business organization.
In 1999, Prestwick Chemical opened a branch near Strasbourg, then hosted by the Faculty of Pharmacy from the Louis Pasteur University with 3 employees. In 2001, Prestwick Chemical moved to rented facilities with 10 chemistry benches. In 2004, Prestwick Chemical completed the construction of its current facilities, hosting 32 benches with extension to 48 possible.