Medicinal Chemistry Services

Hit discovery

Virtual Hit Identification

Based on X-ray structures and/or known active ligands, our computational and medicinal chemistry experts perform a pharmacophore-based virtual screening to identify new hits for a biological target or a specific mechanism. This service has been designed as a product (SaaP) and includes the following tasks:



    PRESTWICK CHEMICAL Literature/project search and analysis
    PRESTWICK CHEMICAL Pharmacophore model generation, optimization and validation
    PRESTWICK CHEMICAL Virtual screening with several and specific compound databases (10+ Mio)
    PRESTWICK CHEMICAL Virtual hit analysis and selection for biochemical evaluation

Our innovative solution is aimed to solve the difficulty of finding a new starting point and allow customer to save time and money by avoiding medium or high-throughput screening (HTS). From our experience, hit rate is raised by 20%.



OPTIMAL RELATIONSHIP WITH CUSTOMERS


  • Concerted dialog through regular reports and meetings to ensure optimal responsiveness
  • Flexibility and versatility to adapt to project timelines and objectives
  • Personalized contract including FTE-based or objective driven programs to meet customer's needs
  • Compliance with confidentiality agreements confirmed by external audits
  • Full transparency towards customers
  • Exclusive assignment of Industrial Property to customers
  • Conformity of all delivered compounds validated by our quality control department
  • Compliance with health and safety rules confirmed by external audits
  • Respect for environmental and social standards


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40
PROJECTS

10 compounds
IN CLINICAL PHASE

1 COMPOUND
ON THE MARKET

650 Clients
FOR THE LIBRARIES

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