Virtual Hit Identification
Based on X-ray structures and/or known active ligands, our computational and medicinal chemistry experts perform a pharmacophore-based virtual screening to identify new hits for a biological target or a specific mechanism. This service has been designed as a product (SaaP) and includes the following tasks:
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Literature/project search and analysis |
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Pharmacophore model generation, optimization and validation |
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Virtual screening with several and specific compound databases (10+ Mio) |
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Virtual hit analysis and selection for biochemical evaluation |
Our innovative solution is aimed at solving the difficulty of finding a new starting point and allow customers to save time and money by avoiding medium or high-throughput screening (HTS). From our experience, hit rate is raised by 20%.
Virtual Hit Identification
- DELIVERABLE:
project report, pharmacophore models
and virtual hit lists - OVERALL DURATION:
8 weeks
from 12 800 EUR / USD
OPTIMAL RELATIONSHIP WITH CUSTOMERS
- Concerted dialog through regular reports and meetings to ensure optimal responsiveness
- Versatility and flexible adaptation to project timelines and objectives
- Personalized contract including FTE-based or objective driven programs to meet customer's needs
- Compliance with confidentiality agreements confirmed by external audits
- Full transparency towards customers
- Exclusive assignment of Industrial Property to customers
- Conformity of all delivered compounds validated by our quality control department
- Compliance with health and safety rules confirmed by external audits
- Respect for environmental and social standards
Medicinal Chemistry SERVICES
