The complexity of CNS diseases, the challenge of central drug delivery in combination with the high attrition rate of therapeutic candidates during development make CNS drug approval more difficult compared to other therapeutic areas. To help you identify high-quality hits, 320 structurally diverse approved drugs were carefully selected by a pharmacist-chemist team for their known pharmacological effects on the Central Nervous System.
This Library will be a useful tool for the discovery of compounds dedicated to the treatment of brain diseases, such as brain tumors, mental disorders, and neurodegenerative diseases.
CNS-penetrant Drug Library: A unique and diversified library of approved CNS-drugs
Structurally diverse, medicinally active, CNS-penetrant and cell permeable compounds
Certified pharmacological effect on the central nervous system
High degree of diversity in terms of biological targets (see below)
Large panel of therapeutic uses
High-quality hits guaranteed, suitable for chemical optimization
Small molecule drugs (mean MW: 290)
Constant in-house quality control ensuring high purity and stable compounds