Prestwick Chemical Library® : new library of 1520 approved drugs
A team of medicinal chemists and pharmacists selected a collection of 1520 off-patent drugs with high chemical and pharmacological diversity, as well as known bioavailability and safety in humans.
Prestwick Chemical Library® : Key features
- A unique collection of 1520 off-patent small molecules, 99% approved drugs (FDA, EMA and other agencies)
- High chemical and pharmacological diversity (WHO ATC Classification 5)
- More than 400 targets addressed
- Specially designed to increase potential high-quality hits – Mean MW: 383
- Over the past 20 years, hit-likeness and hit-workability have been reported by users in 400+ publications
- A constant in-house quality control ensures high purity and stable compounds Including a database with newly identified targets and New Application data
Prestwick Chemical Library® : How provided?
- In powder form, 10-100mg with cherry-picking options
- In DMSO at 10mM, ready for screening (100µL – 1mL)
- In 96 or 384 Well format or plates of your choice
- Optional 2D barcodes
- Customization volume/mapping
- Stability 5 years at -20°C
- Database annotation includes target, therapeutic class/effect, side effects, patent and ADMET information
- Re-supply of any hit-compound up to 100 mg
Prestwick Chemical Library® : Applications
- Assay validation
- Repurposing/ repositioning
- Start of new optimization process
- Finding of stem cell growth modulators
- Others…
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