Prestwick Chemical Library®

NEW LIBRARY OF 1520 APPROVED DRUGS

A team of medicinal chemists and pharmacists selected a collection of 1520 off-patent drugs with high chemical and pharmacological diversity, as well as known bioavailability and safety in humans.

 

Key features

  • A unique collection of 1520 off-patent small molecules, 99% approved drugs (FDA, EMA and other agencies)
  • High chemical and pharmacological diversity (WHO ATC Classification 5)
  • More than 400 targets addressed
  • Specially designed to increase potential high-quality hits – Mean MW: 383
  • Over the past 20 years, hit-likeness and hit-workability have been reported by users in 400+ publications
  • A constant in-house quality control ensures high purity and stable compounds Including a database with newly identified targets and New Application data

WHO ATC Classification 5

How provided?

  • In powder form, 10-100mg with cherry-picking options
  • In DMSO at 10mM, ready for screening (100µL – 1mL)
  • In 96 or 384 Well format or plates of your choice
  • Optional 2D barcodes
  • Customization volume/mapping
  • Stability 5 years at -20°C
  • Database annotation includes target, therapeutic class/effect, side effects, patent and ADMET information
  • Re-supply of any hit-compound up to 100 mg

 

Applications

  • Assay validation
  • Repurposing/ repositioning
  • Start of new optimization process
  • Finding of stem cell growth modulators
  • Others…

 

MAIN TARGETS

 

Request a quote