Publications

Publications
Haloperidol inactivates AMPK and reduces tau phosphorylation in a tau mouse model of Alzheimer’s disease
Alzheimer's and Dementia: Translational Research and Clinical Interventions

 Koppel J, Jimenez H, Adrien L, Greenwald B, Marambaud P, Cinamon E, Davies P
 Alzheimer's and Dementia: Translational Research and Clinical Interventions - vol. 2 121-130 (2016)

? 2016 The AuthorsIntroduction The use of antipsychotic medications in Alzheimer’s disease has been associated with an increased risk of mortality in clinical trials. However, an older postmortem literature suggests that those with schizophrenia treated in an era of exclusively conventional antipsychotic medications had a surprisingly low incidence of tau pathology. No previously published studies […]

Publications
Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine ␤ -synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon
Pharmacological Research

 Druzhyna N, Szczesny B, Olah G, Módis K, Asimakopoulou A, Pavlidou A, Szoleczky P, Gerö D, Yanagi K, Törö G, López-garcía I, Myrianthopoulos V, Mikros E, Zatarain JR, Chao C, Papapetropoulos A, Hellmich MR, Szabo C
 Pharmacological Research - vol. 113 18-37 (2016)

Publications
Characterization and application of two RANK-specific antibodies with different biological activities
Immunology Letters

 Chypre M, Seaman J, Cordeiro OG, Willen L, Knoop KA, Buchanan A, Sainson RCA, Williams IR, Yagita H, Schneider P, Mueller CG
 Immunology Letters - vol. 171 5-14 (2016)

Antibodies play an important role in therapy and investigative biomedical research. The TNF-family member Receptor Activator of NF-??B (RANK) is known for its role in bone homeostasis and is increasingly recognized as a central player in immune regulation and epithelial cell activation. However, the study of RANK biology has been hampered by missing or insufficient […]

Publications
A Yeast/Drosophila Screen to Identify New Compounds Overcoming Frataxin Deficiency
Oxidative Medicine and Cellular Longevity

 Seguin A, Monnier VV, Palandri A, Bihel FF, Rera M, Schmitt M, Camadro JM, Tricoire HH, Lesuisse E
 Oxidative Medicine and Cellular Longevity - vol. ID 565140 1-11 (2015)

Friedreich’s ataxia (FA) is a rare neurodegenerative disease which is very debilitating for the patients who progressively lose their autonomy. The lack of efficient therapeutic treatment of the disease strongly argues for urgent need to search for new active compounds that may stop the progression of the disease or prevent the appearance of the symptoms […]

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