Identification of Drug Transporter Genomic Variants and Inhibitors

That Protect Against Doxorubicin-Induced Cardiotoxicity

Multiple pharmacogenomic studies have identified the synonymous genomic variant rs7853758 (G > A, L461L) and the intronic variant rs885004 in SLC28A3 (solute carrier family 28 member 3) as statistically associated with a lower incidence of anthracycline-induced cardiotoxicity

link to reference