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Publications
Kinetic-Based High-Throughput Screening Assay to Discover Novel Classes of Macrophage Migration Inhibitory Factor Inhibitors

Journal of Biomolecular Screening

Ouertatani-Sakouhi H, Liu M, El-Turk F, Cuny GD, Glicksman MA, Lashuel HA
Journal of Biomolecular Screening - vol. 15 347-358 (2010)

Publications
Pharmacophores in drug research

Molecular Informatics

Langer T
Molecular Informatics - vol. 29 470-475 (2010)

The pharmacophore concept in modern drug research is highlighted and the most important use examples and success stories are reviewed. These include papers from method development as well as from application areas. As indicated by the number of publications available, the pharmacophore approach has proven to be extremely useful as interface between medicinal and computational […]

Publications
NIH Public Access

Tuberculosis

Manuscript A, Leads PD
Tuberculosis - vol. 89 331-333 (2010)

Publications
Biochimie Mode of action of the antiprion drugs 6AP and GA on ribosome assisted protein folding

Biochimie

Dos S, Pang Y, Vishnu N, Voisset C, Galons H, Blondel M, Sanyal S
Biochimie - vol. 93 1047-1054 (2011)

Publications
Are pyridazines privileged structures?

MedChemComm

Wermuth CG
MedChemComm - vol. 2 935 (2011)

One can estimate that about 50% of all the drug molecules used in medicine contain a phenyl ring which can be substituted or not. The bioisosteric replacement of these phenyl rings by the corresponding pyridazine rings opens an access to several thousands of diaza analogues presenting more interaction possibilities, lower Log P values and improved […]

Publications
P.4.11 Developing therapies for congenital myopathies by high throughput chemical screening in ryanodine receptor 1 mutant zebrafish

Neuromuscular Disorders

Gupta V, Kuwada J, Beggs A
Neuromuscular Disorders - vol. 23 762-763 (2013)

Publications
Label-Free Quantitative Mass Spectrometry Reveals Novel Pathways Involved in LL-37 Expression

Journal of Innate Immunity

Cederlund A, Nylén F, Miraglia E, Bergman P, Gudmundsson GH, Agerberth B
Journal of Innate Immunity 365-376 (2013)

Publications
Structure − Activity Relationship Study around Guanabenz Identifies Two Derivatives Retaining Antiprion Activity but Having Lost α 2- Adrenergic Receptor Agonistic Activity

ACS Chem. Neurosci. 2014,

Nguyen P, Hammoud H, Halliez S, Pang Y, Evrard J, Blondel M, Strasbourg UD, De F
ACS Chem. Neurosci. 2014, - vol. 5 1075-1082 (2014)

Publications
Phenotypic Screens Targeting Neurodegenerative Diseases

Journal of Biomolecular Screening

Zhang M, Luo G, Zhou Y, Wang S, Zhong Z
Journal of Biomolecular Screening - vol. 19 1-16 (2014)

Publications
Immunomodulatory activity of commonly used drugs on Fc-receptor-mediated human natural killer cell activation

Cancer Immunology, Immunotherapy

Theorell J, Gustavsson AL, Tesi B, Sigmundsson K, Ljunggren HG, Lundbäck T, Bryceson YT
Cancer Immunology, Immunotherapy - vol. 63 627-641 (2014)